I have always preferred to open the batting and I think there are many good reasons to do it. There is rarely a queue for the job, so your skipper and your team mates will be grateful to you for stepping up, and will usually make allowances for a volunteer opener that they might not make for others. In particular, you have the opportunity of time. In the club cricket I play (40-50 overs), openers are not expected to score quickly, and if one considers the primary function to be to see off the opening bowlers, it can be that you are either 20* or 40* off 15 overs and neither will be seen as a problem. Once you get in, your scoring rate will increase naturally, if you get out you will still get respect for stepping up against the best bowlers and the new ball.
From a technical perspective, the key adjustment I have made in recent years is to take a Middle-and-Off guard. As an opener one is always facing the new ball, so swing either way is generally less of an issue. Facing standard medium/fast seam bowling, taking Middle-and-Off enables me to get comfortably inside leg stump deliveries, allowing me to score all around the wicket more freely. I have struggled with leg side shots in the past, but now I am considerably more confident at gliding or turning the ball between Midwicket and Fine-leg. Once I get in, this begins to include deliveries on Middle-and-Leg or Middle, which has the added benefit of frustrating seam bowlers.
You should note that I am Right-handed, for a left hander the adjustment may open up your leg stump too much to the natural line of a Right-arm over bowler. Best to try in the nets first, to see if the guard suits you.